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Test Mnemonic DSG13 Desmoglein 1 (DSG1) and Desmoglein 3 (DSG3), IgG Antibodies, Serum

Reporting Name

Desmoglein 1 and 3, S

Useful For

Preferred screening test for patients suspected to have an autoimmune blistering disorder of the skin or mucous membranes (pemphigus)

 

As an aid in the diagnosis of pemphigus

Performing Laboratory

Mayo Medical Laboratories in Rochester

Specimen Type

Serum


Specimen Required


Container/Tube: 

Preferred: Red top

Acceptable: Serum gel

Specimen Volume: 1 mL


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 14 days
  Frozen  30 days
  Ambient  36 hours

Reference Values

DESMOGLEIN 1

<14.0 U (negative)

14.0-20.0 U (indeterminate)

>20.0 U (positive)

 

DESMOGLEIN 3

<9.0 U (negative)

9.0-20.0 U (indeterminate)

>20.0 U (positive)

Day(s) and Time(s) Performed

Once per week, Monday through Friday, day of testing determined by laboratory

Test Classification

This test has been modified from the manufacturer's instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

83516 x 2

LOINC Code Information

Test ID Test Order Name Order LOINC Value
DSG13 Desmoglein 1 and 3, S 43309-4

 

Result ID Test Result Name Result LOINC Value
83680 DSG 1 43311-0
24027 DSG 3 43312-8

Method Name

Enzyme-Linked Immunosorbent Assay (ELISA)