Sign in →

Test Mnemonic JAK2 EXON JAK2 Exon 12-14

Performing Laboratory

NeoGenomics Laboratories

Methodology & Test Description

Molecular

 

RT-PCR and bi-directional sequencing to detect non-V617F mutations in exons 12-14 and most of exon 15, corresponding to the majority of the JAK2 pseudokinase domain. Exon deletion mutations are detectable. Testing is performed on plasma for increased sensitivity whenever possible. V617F analysis is recommended before or concurrently with this test. Exon 12-14 Mutation Analysis may be ordered separately, with concurrent V617F testing, by reflex after negative V617F testing, or as part of the MPN Reflex Panel.

 

 

Physician Office Specimen Requirements

Peripheral Blood

Container/Tube:  Lavender-top (EDTA) tube(s)

Specimen:  5 mL of EDTA whole blood

Transport Temperature:  Refrigerate

Collection Instructions:  Be sure cold pack is not in direct contact with specimen during transport.

JAK2 Exon 12-14 only: 81403. JAK2 V617F and Exon 12-14 run concurrently or by reflex: 81270, 81403

Note:  See “NeoGenomics” in “Request Forms”.

 

 

 

Reference Values

An interpretive report will be provided.

Test Classification and CPT Coding

JAK2 Exon 12-14 only: 81403. JAK2 V617F and Exon 12-14 run concurrently or by reflex: 81270, 81403

 

Special Instructions