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Test Mnemonic URIC Uric Acid, Serum

Methodology

Clinical Significance:

Elevations occur in gout, renal diseases with renal failure, dehydration, diuretic use, alcoholism, lead poisoning, lymphoma leukemia, mononucleosis, acute inflammatory states acidosis. Used as indicator of renal vascular involvement in essential hypertension. Elevated uric acid may also be the result of massive nucleic acid catabolism such as occurs in toxemia of pregnancy and chemotherapy or radiation therapy of tumors. Causes of low uric acid include Wilson’s disease, Fanconi syndrome, obstructive biliary disease, and syndrome of inappropriate secretion of antidiuretic hormone.

Performing Laboratory

Hallmark Health

Physician Office Specimen Requirements

Container/Tube:  Serum gel tube(s)

Specimen:  1 mL of serum

Transport Temperature:  Refrigerate

Reference Values

Males:  3.4-7.0 mg/dL

Females:  2.4-6.0 mg/dL

Additional Information

Limitations:

Positive interferences may be caused by ascorbic acid, caffeine, theophylline, theobromine, high serum glucose, 2-methyldopa, and L-dopa. EDTA, sodium fluoride, and sodium citrate interfere.