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Test Mnemonic JAK2 V617F JAK2 V617F

Methodology & Test Description



Detects the V617F mutation. The rare mutation V617I is also detected. Testing is performed on plasma for increased sensitivity whenever possible. V617F testing may be ordered separately, concurrently with full exon 12-14 sequencing, with reflex to exon 12-14 sequencing, or as part of the MPN Reflex Panel.

Performing Laboratory

NeoGenomics Laboratories

Physician Office Specimen Requirements

Peripheral Blood

Container/Tube:  Lavender-top (EDTA) tube(s)

Specimen:  1 mL to 2 mL of EDTA whole blood

Transport Temperature:  Refrigerate

Collection Instructions:  Be sure cold pack is not in direct contact with specimen during transport.

Note:  See “NeoGenomics” in “Request Forms”.




Reference Values

An interpretive report will be provided.

Test Classification and CPT Coding

JAK2 V617F only: 81270. JAK2 V617F and Exon 12-14 run concurrently or by reflex: 81270, 81403

Special Instructions