Test Mnemonic LACO Lacosamide, Serum
Useful For
Monitoring serum concentrations of lacosamide to ensure compliance and appropriate dosing in specific clinical conditions (ie, severe renal impairment, mild-to-moderate hepatic impairment, and end-stage renal disease)
Reporting Name
Lacosamide, SSpecimen Type
SerumSpecimen Required
Container/Tube:
Preferred: Red top
Acceptable: Serum gel
Specimen Volume: 1 mL
Collection Instructions: Draw specimen immediately before next scheduled dose or at least 12 hours after last dose.
Specimen Minimum Volume
0.2 mL
Specimen Stability Information
Specimen Type | Temperature | Time |
---|---|---|
Serum | Refrigerated (preferred) | 28 days |
Ambient | 28 days | |
Frozen | 28 days |
Reference Values
Patients receiving therapeutic doses usually have lacosamide concentrations of 1.0-10.0 mcg/mL.
Day(s) and Time(s) Performed
Monday through Friday; 9 a.m., Saturday; 1 p.m.
Performing Laboratory

Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.CPT Code Information
80299
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
LACO | Lacosamide, S | 59297-2 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
62772 | Lacosamide, S | 59297-2 |
Method Name
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)